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Ataxin 1 antibody (AA 645-815)

Name: Ataxin 1 antibody (AA 645-815)
Brand: antibodies-online
SKU: ABIN7193321
Price: 511.5 USD
Availability: InStock

ATXN1 Reactivity: Human, Mouse, Rat, Monkey WB, IHC, ELISA, ICC, FACS, Neut Host: Mouse Monoclonal 4C7B11 unconjugated

Western blot analysis using ATXN1 mAb against human ATXN1 (AA: 645-815) recombinant protein.

Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using ATXN1 mouse mAb with DAB staining.

IHC

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng)

ELISA

Western blot analysis using ATXN1 mAb against HEK293 (1) and ATXN1 (AA: 645-815)-hIgGFc transfected HEK293 (2) cell lysate.

Western blot analysis using ATXN1 mouse mAb against C6 (1), COS7 (2), NIH/3T3 (3), and HL-60 (4) cell lysate.

Flow cytometric analysis of Jurkat cells using ATXN1 mouse mAb (green) and negative control (red).

FACS

6 images

Catalog No. ABIN7193321

Datasheet as PDF

Target See all Ataxin 1 (ATXN1) Antibodies

Ataxin 1 (ATXN1)
Binding Specificity
28

20

18

11

7

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 645-815
Reactivity
76

60

35

2

1

1

1

1

1

1
Human, Mouse, Rat, Monkey
Host
66

45

1
Mouse
Compatible Secondaries
Clonality
67

45
Monoclonal
Conjugate
43

8

7

7

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2
This Ataxin 1 antibody is un-conjugated
Application
84

45

33

33

30

23

23

22

9

6

3

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification

purified

Immunogen

Purified recombinant fragment of human ATXN1 (AA: 645-815) expressed in E. coli.

Clone

4C7B11

Isotype

IgG1
anti-Ataxin 1 (ATXN1) antibody
ATXN1 Reactivity: Human WB, IHC, ELISA, ICC, FACS Host: Mouse Monoclonal 2F5 unconjugated

anti-Ataxin 1 (ATXN1) (AA 645-815) antibody
ATXN1 Reactivity: Human, Mouse WB, IHC, ELISA, ICC, FACS, Neut Host: Mouse Monoclonal 2B8A2 unconjugated

anti-Ataxin 1 (ATXN1) (AA 569-807) antibody
ATXN1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Ataxin 1 (ATXN1) (C-Term) antibody
ATXN1 Reactivity: Human, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Ataxin 1 (ATXN1) (AA 331-587) antibody
ATXN1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Ataxin 1 (ATXN1) (AA 346-475) antibody
ATXN1 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Ataxin 1 (ATXN1) antibody
ATXN1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Ataxin 1 (ATXN1) (AA 164-197) antibody
ATXN1 Reactivity: Mouse WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S76-8 unconjugated

anti-Ataxin 1 (ATXN1) (AA 746-761) antibody
ATXN1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal S65-37 unconjugated

anti-Ataxin 1 (ATXN1) (AA 164-197) antibody (HRP)
ATXN1 Reactivity: Mouse WB, IHC, IF, IP, ICC Host: Mouse Monoclonal S76-8 HRP

Application Notes

ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: 1:200 - 1:1000

Restrictions

For Research Use only
Buffer

Purified antibody in PBS with 0.05 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

4°C, -20°C for long term storage
Target

Ataxin 1 (ATXN1)

Alternative Name

ATXN1 (ATXN1 Products)

Synonyms

ATX1 antibody, D6S504E antibody, SCA1 antibody, ATXN1 antibody, ataxin 1b antibody, atxn1 antibody, 2900016G23Rik antibody, Atx1 antibody, C85907 antibody, ENSMUSG00000074917 antibody, Gm10786 antibody, Sca1 antibody, CG4547 antibody, Dmel\\CG4547 antibody, dAtx-1 antibody, dAtx1 antibody, sca1 antibody, ataxin 1 antibody, ataxin 1b antibody, Ataxin 1 antibody, ATXN1 antibody, atxn1b antibody, Atxn1 antibody, Atx-1 antibody

Background

Description: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 40-83 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). Alternative splicing results in multiple transcript variants, with one variant encoding multiple distinct proteins, ATXN1 and Alt-ATXN1, due to the use of overlapping alternate reading frames.
Aliases: ATX1, SCA1, D6S504E

Molecular Weight

86.9 kDa

Gene ID

6310

Pathways

Synaptic Membrane