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SECTM1 Protein (AA 29-145) (Fc Tag)

SECTM1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275555
  • Target See all SECTM1 Proteins
    SECTM1 (Secreted and Transmembrane 1 (SECTM1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-145
    Origin
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SECTM1 protein is labelled with Fc Tag.
    Purpose
    Human SECTM1 Protein
    Sequence
    Gln29-Gly145
    Characteristics
    Recombinant Human SECTM1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln29-Gly145.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SECTM1 (Secreted and Transmembrane 1 (SECTM1))
    Alternative Name
    SECTM1 (SECTM1 Products)
    Synonyms
    K12 Protein, secreted and transmembrane 1 Protein, SECTM1 Protein
    Background
    SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.
    Molecular Weight
    39.4 kDa. Due to glycosylation, the protein migrates to 47-50 kDa based on Tris-Bis PAGE result.
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