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PYGL antibody

PYGL Reactivity: Human, Rat, Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7237619
  • Target See all PYGL Antibodies
    PYGL (phosphorylase, Glycogen, Liver (PYGL))
    Reactivity
    • 47
    • 19
    • 12
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 54
    • 2
    Rabbit
    Clonality
    • 54
    • 2
    Polyclonal
    Conjugate
    • 19
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PYGL antibody is un-conjugated
    Application
    • 28
    • 17
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human PYGL
    Isotype
    IgG
    Top Product
    Discover our top product PYGL Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:30-1:150
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PYGL (phosphorylase, Glycogen, Liver (PYGL))
    Alternative Name
    PYGL (PYGL Products)
    Synonyms
    zgc:66314 antibody, GSD6 antibody, glycogen phosphorylase L antibody, phosphorylase, glycogen, liver antibody, phosphorylase, glycogen, liver S homeolog antibody, liver glycogen phosphorylase antibody, PYGL antibody, pygl antibody, pygl.S antibody, Pygl antibody
    Background
    This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.
    Molecular Weight
    97 kDa
    UniProt
    P06737
    Pathways
    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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