IFIH1 antibody (AA 1-205)
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- Target See all IFIH1 Antibodies
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
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Binding Specificity
- AA 1-205
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IFIH1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- MSNGYSTDEN FRYLISCFRA RVKMYIQVEP VLDYLTFLPA EVKEQIQRTV ATSGNMQAVE LLLSTLEKGV WHLGWTREFV EALRRTGSPL AARYMNPELT DLPSPSFENA HDEYLQLLNL LQPTLVDKLL VRDVLDKCME EELLTIEDRN RIAAAENNGN ESGVRELLKR IVQKENWFSA FLNVLRQTGN NELVQELTGS DCSES
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human IFIH1 (NP_071451.2).
- Isotype
- IgG
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anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibody
IFIH1 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (N-Term) antibodyVerified IFIH1 Reactivity: Human, Monkey WB, ELISA, IHC, FACS Host: Goat Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 700-1025) antibodyIFIH1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-221) antibodyIFIH1 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) antibodyIFIH1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 928-1023) antibodyIFIH1 Reactivity: Human ELISA, IHC (p) Host: Mouse Monoclonal 3F6 unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 612-661) antibodyIFIH1 Reactivity: Human, Mouse, Rat, Cow, Horse, Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 Reactivity: Human, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (Middle Region) antibodyIFIH1 Reactivity: Human, Mouse, Rat, Cow, Horse, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
- Alternative Name
- IFIH1 (IFIH1 Products)
- Synonyms
- MDA5 antibody, Hlcd antibody, IDDM19 antibody, MDA-5 antibody, RLR-2 antibody, 9130009C22Rik antibody, Helicard antibody, RGD1560496 antibody, interferon induced with helicase C domain 1 antibody, IFIH1 antibody, Ifih1 antibody
- Background
- DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.,IFIH1,AGS7,Hlcd,IDDM19,MDA-5,MDA5,RLR-2,SGMRT1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,Cytokines,Interferons,Cell Intrinsic Innate Immunity Signaling Pathway,IFIH1
- Molecular Weight
- 25 kDa/116 kDa
- Gene ID
- 64135
- UniProt
- Q9BYX4
- Pathways
- Activation of Innate immune Response
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