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RHBDF1 antibody (N-Term)

RHBDF1 Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783869
  • Target See all RHBDF1 Antibodies
    RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))
    Binding Specificity
    • 4
    • 1
    • 1
    N-Term
    Reactivity
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 7
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    This RHBDF1 antibody is un-conjugated
    Application
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    KDWEKAPEQA DLTGGALDRS ELERSHLMLP LERGWRKQKE GAAAPQPKVR
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against RHBDF1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human RHBDF1
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 855 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))
    Alternative Name
    RHBDF1 (RHBDF1 Products)
    Synonyms
    zgc:91984 antibody, C16orf8 antibody, Dist1 antibody, EGFR-RS antibody, gene-89 antibody, gene-90 antibody, hDist1 antibody, C16ORF8 antibody, Dist antibody, Egfr-rs antibody, mKIAA4242 antibody, rhomboid 5 homolog 1 antibody, rhomboid 5 homolog 1a (Drosophila) antibody, RHBDF1 antibody, rhbdf1 antibody, rhbdf1a antibody, Rhbdf1 antibody
    Background
    RHBDF1 is a seven-transmembrane protein with a long N-terminal cytoplasmic extension that comprises half of the polypeptide sequence, and is found in the endoplasmic reticulum and Golgi, but not on the cell surface. RHBDF1 has a pivotal role in sustaining growth signals in epithelial cancer cells and thus may serve as a therapeutic target for treating epithelial cancers.
    Alias Symbols: C16orf8, Dist1, EGFR-RS, FLJ2235, FLJ22357, gene -89, gene -90, hDist1, gene-89, gene-90
    Protein Interaction Partner: UBC, TGFA,
    Protein Size: 855
    Molecular Weight
    97 kDa
    Gene ID
    64285
    NCBI Accession
    NM_022450, NP_071895
    UniProt
    Q96CC6
    Pathways
    EGFR Signaling Pathway, Growth Factor Binding
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