SIRT2 antibody (Middle Region)
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- Target See all SIRT2 Antibodies
- SIRT2 (Sirtuin 2 (SIRT2))
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Binding Specificity
- AA 165-187, Middle Region
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIRT2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for NAD-dependent protein deacetylase sirtuin-2(SIRT2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequence
- YTQNIDTLER IAGLEQEDLV EAH
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for NAD-dependent protein deacetylase sirtuin-2(SIRT2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: sirtuin 2
Protein Name: NAD-dependent protein deacetylase sirtuin-2 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human SIRT2(165-187aa YTQNIDTLERIAGLEQEDLVEAH), different from the related mouse and rat sequences by three amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SIRT2 Primary Antibody
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anti-Sirtuin 2 (SIRT2) (AA 288-389) antibody
SIRT2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 128-227) antibodySIRT2 Reactivity: Human WB, ELISA, IF, RNAi Host: Mouse Monoclonal 4B11 unconjugated
anti-Sirtuin 2 (SIRT2) (AA 28-303) antibodySIRT2 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 65-340) antibodySIRT2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 65-340) antibodySIRT2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (C-Term) antibodySIRT2 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) antibodySIRT2 Reactivity: Human, Rat, Mouse WB, IF Host: Mouse Monoclonal 1D4-H11-H11 unconjugated
anti-Sirtuin 2 (SIRT2) (AA 275-389) antibodySIRT2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 5H11H9 unconjugated
anti-Sirtuin 2 (SIRT2) (C-Term) antibodySIRT2 Reactivity: Human, Rat, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 177-279) antibodySIRT2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for SIRT2 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- SIRT2 (Sirtuin 2 (SIRT2))
- Alternative Name
- SIRT2 (SIRT2 Products)
- Synonyms
- CG5085 antibody, D.mel2 antibody, Dmel\\CG5085 antibody, SIRT2 antibody, dSIRT2 antibody, sir2 antibody, Sirt2 antibody, BmSirt2 antibody, AtSRT2 antibody, SIRTUIN 2 antibody, T2K12.8 antibody, sirtuin 2 antibody, SIR2 antibody, SIR2L antibody, SIR2L2 antibody, 5730427M03Rik antibody, Sir2l antibody, wu:fb57d05 antibody, zgc:55966 antibody, zgc:77003 antibody, Sirtuin 2 antibody, sirtuin 2 antibody, sirtuin 2 S homeolog antibody, NAD-dependent deacetylase sirtuin 2 homolog antibody, sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) antibody, Sirt2 antibody, SIRT2 antibody, sirt2.S antibody, SRT2 antibody, sirt2 antibody
- Background
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SIRT2 is a predominantly cytoplasmic protein that colocalizes with microtubules. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT2 is mapped to 19q13.2. It is able to cause radioactivity to be transferred from (32P) NAD to bovine serum albumin (BSA). According to researches, SIRT2 can act as a bona fide tubulin deacetylase. SIRT2 was found to deacetylate lys40 of alpha-tubulin both in vitro and in vivo. SIRT2 is also a regulator of mitotic progression that acts downstream from CDC14B in a pathway regulating mitotic exit or subsequent cytokinesis. What's more, SIRT2 is an important regulator of programmed necrosis.
Synonyms: FLJ35621 antibody|FLJ37491 antibody|NAD dependent deacetylase sirtuin 2 antibody|NAD-dependent deacetylase sirtuin-2 antibody|NAD-dependent protein deacetylase sirtuin-2 antibody|Regulatory protein SIR2 homolog 2 antibody|Silencing information regulator 2 like antibody|Silent information regulator 2 antibody|Silent mating type information regulation 2 antibody|Silent mating type information regulation 2 homolog antibody|SIR 2 antibody|SIR2 antibody|SIR2 like antibody|SIR2 like protein 2 antibody|Sir2 related protein type 2 antibody|SIR2, S. cerevisiae, homolog-loke 2 antibody|SIR2-like protein 2 antibody|SIR2L antibody|SIR2L2 antibody|SIRT 2 antibody|SIRT2 antibody|SIRT2_HUMAN antibody|Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae) antibody|Sirtuin 2 antibody|Sirtuin type 2 antibody|Sirtuin2 antibody - Gene ID
- 22933
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