VPS16 antibody (AA 7-89)
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- Target See all VPS16 Antibodies
- VPS16 (Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16))
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Binding Specificity
- AA 7-89
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VPS16 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Rat
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human VPS16 protein (7-89AA)
- Isotype
- IgG
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anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (Internal Region) antibody
Verified VPS16 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 754-839) antibodyVPS16 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2F10 unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (Internal Region) antibodyVPS16 Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (C-Term) antibodyVPS16 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (Internal Region) antibodyVerified VPS16 Reactivity: Human, Mouse WB, ELISA Host: Goat Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) antibodyVPS16 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 1-839) antibodyVPS16 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 587-636) antibodyVPS16 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Pig, Bat, Monkey, Hamster WB Host: Rabbit Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (C-Term) antibodyVPS16 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Pig, Bat, Monkey, Hamster WB Host: Rabbit Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16) (AA 540-839) antibodyVPS16 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- VPS16 (Vacuolar Protein Sorting-Associated Protein 16 Homolog (VPS16))
- Alternative Name
- VPS16 (VPS16 Products)
- Synonyms
- 1810074M16Rik antibody, hVPS16 antibody, VPS16A antibody, vacuolar protein sorting protein 16 antibody, Vacuolar protein sorting-associated protein 16 homolog antibody, VSP16 CORVET/HOPS core subunit antibody, VPS16, CORVET/HOPS core subunit antibody, vacuolar protein sorting 16 homolog (S. cerevisiae) antibody, VPS16 CORVET/HOPS core subunit antibody, Tc00.1047053506367.60 antibody, Tc00.1047053508355.200 antibody, vps-16 antibody, Vps16 antibody, VPS16 antibody
- Background
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Background: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for recruitment of VPS33A to the HOPS complex (PubMed:23901104). Required for fusion of endosomes and autophagosomes with lysosomes, the function is dependent on its association with VPS33A but not VPS33B (PubMed:25783203). The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG (PubMed:24554770).
Aliases: Vacuolar protein sorting-associated protein 16 homolog (hVPS16), VPS16
- UniProt
- Q6GMQ7
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