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BAD antibody (pSer155)

BAD Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256155
  • Target See all BAD Antibodies
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    Binding Specificity
    • 34
    • 34
    • 27
    • 27
    • 26
    • 24
    • 24
    • 22
    • 15
    • 11
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    pSer155
    Reactivity
    • 383
    • 222
    • 145
    • 17
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 459
    • 15
    • 1
    Rabbit
    Clonality
    • 441
    • 34
    Polyclonal
    Conjugate
    • 180
    • 43
    • 38
    • 38
    • 36
    • 33
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This BAD antibody is un-conjugated
    Application
    • 257
    • 256
    • 163
    • 103
    • 81
    • 80
    • 57
    • 55
    • 22
    • 18
    • 12
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Phospho-BAD (Ser155) Antibody detects endogenous levels of BAD only when phosphorylated at Ser118, which site historically referenced as Ser155.
    Predicted Reactivity
    Bovine,Horse,Sheep,Dog
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human BAD around the phosphorylation site of Ser155.
    Isotype
    IgG
    Top Product
    Discover our top product BAD Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    Alternative Name
    BAD (BAD Products)
    Synonyms
    bad antibody, fa01b12 antibody, wu:fa01b12 antibody, wu:fa96d04 antibody, BAD antibody, BBC2 antibody, BCL2L8 antibody, AI325008 antibody, Bbc2 antibody, BCL2-associated agonist of cell death b antibody, BCL2 associated agonist of cell death antibody, BCL2-associated agonist of cell death antibody, badb antibody, BAD antibody, Bad antibody
    Background

    Description: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

    Gene: BAD

    Molecular Weight
    23kDa
    Gene ID
    572
    UniProt
    Q92934
    Pathways
    MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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