PARP12 antibody (C-Term)
(1 reference)-
- Target See all PARP12 products
- PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))
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Binding Specificity
- AA 454-483, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PARP12 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This Parp12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of mouse Parp12.
- Clone
- RB14194
- Isotype
- Ig Fraction
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anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) (AA 312-344), (N-Term) antibody
PARP12 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) (C-Term) antibodyPARP12 Reactivity: Human, Mouse, Dog, Pig, Rabbit, Cow WB Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) antibodyPARP12 Reactivity: Human IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) (AA 462-701) antibodyPARP12 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) (Middle Region) antibodyPARP12 Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Cow WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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: "Scarless fetal mouse wound healing may initiate apoptosis through caspase 7 and cleavage of PARP." in: The Journal of surgical research, Vol. 156, Issue 1, pp. 74-9, (2009) (PubMed).
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: "Scarless fetal mouse wound healing may initiate apoptosis through caspase 7 and cleavage of PARP." in: The Journal of surgical research, Vol. 156, Issue 1, pp. 74-9, (2009) (PubMed).
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- Target
- PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))
- Alternative Name
- Parp12 (PARP12 Products)
- Synonyms
- ARTD12 antibody, MST109 antibody, MSTP109 antibody, ZC3H1 antibody, ZC3HDC1 antibody, 9930021O16 antibody, AA409132 antibody, AA536654 antibody, PARP-12 antibody, Zc3hdc1 antibody, PARP12 antibody, zc3h1 antibody, mst109 antibody, mstp109 antibody, zc3hdc1 antibody, si:ch211-227d19.2 antibody, poly(ADP-ribose) polymerase family member 12 antibody, poly (ADP-ribose) polymerase family, member 12 antibody, poly(ADP-ribose) polymerase family member 12 L homeolog antibody, poly (ADP-ribose) polymerase family, member 12a antibody, poly [ADP-ribose] polymerase 12 antibody, PARP12 antibody, Parp12 antibody, parp12.L antibody, parp12a antibody, parp12 antibody, LOC100561568 antibody
- Background
- Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
- Molecular Weight
- 79917
- Gene ID
- 243771
- NCBI Accession
- NP_766481
- UniProt
- Q8BZ20
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