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ACD antibody (AA 1-544)

ACD Reactivity: Human WB, ELISA, IP, IF, IHC (p) Host: Mouse Monoclonal 1D8-1B6 unconjugated
Catalog No. ABIN566298
  • Target See all ACD Antibodies
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Binding Specificity
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-544
    Reactivity
    • 30
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    Human
    Host
    • 25
    • 6
    • 1
    Mouse
    Clonality
    • 28
    • 4
    Monoclonal
    Conjugate
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACD antibody is un-conjugated
    Application
    • 21
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against a full length recombinant ACD.
    Sequence
    MPGRCQSDAA MRVNGPASRA PAGWTSGSLH TGPRAGRPRA QARGVRGRGL LLRPRPAKEL PLPRKGGAWA PAGNPGPLHP LGVAVGMAGS GRLVLRPWIR ELILGSETPS SPRAGQLLEV LQDAEAAVAG PSHAPDTSDV GATLLVSDGT HSVRCLVTRE ALDTSDWEEK EFGFRGTEGR LLLLQDCGVH VQVAEGGAPA EFYLQVDRFS LLPTEQPRLR VPGCNQDLDV QKKLYDCLEE HLSESTSSNA GLSLSQLLDE MREDQEHQGA LVCLAESCLT LEGPCTAPPV THWAASRCKA TGEAVYTVPS SMLCISENDQ LILSSLGPCQ RTQGPELPPP DPALQDLSLT LIASPPSSPS SSGTPALPGH MSSEESGTSI SLLPALSLAA PDPGQRSSSQ PSPAICSAPA TLTPRSPHAS RTPSSPLQSC TPSLSPRSHV PSPHQALVTR PQKPSLEFKE FVGLPCKNRP PFPRTGATRG AQEPCSVWEP PKRHRDGSAF QYEYEPPCTS LCARVQAARL PPQLMAWALH FLMDAQPGSE PTPM
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    ACD (AAH16904, 1 a.a. ~ 544 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1D8-1B6
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Frank, Tran, Qu, Stohr, Segal, Xu: "The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres." in: PLoS genetics, Vol. 11, Issue 7, pp. e1005410, (2015) (PubMed).

    Abreu, Aritonovska, Reichenbach, Cristofari, Culp, Terns, Lingner, Terns: "TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo." in: Molecular and cellular biology, Vol. 30, Issue 12, pp. 2971-82, (2010) (PubMed).

  • Target
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Alternative Name
    ACD (ACD Products)
    Synonyms
    PIP1 antibody, PTOP antibody, TINT1 antibody, TPP1 antibody, ACD antibody, ACD, shelterin complex subunit and telomerase recruitment factor antibody, adrenocortical dysplasia antibody, ACD antibody, Acd antibody
    Background
    Full Gene Name: adrenocortical dysplasia homolog (mouse)
    Synonyms: PIP1,PTOP,TINT1,TPP1
    Gene ID
    65057
    Pathways
    Telomere Maintenance
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