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SLC1A2 antibody (N-Term)

Name: SLC1A2 antibody (N-Term)
SKU: ABIN2778148
Price: 472.77 USD
Availability: InStock

SLC1A2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Sheep WB, IHC Host: Rabbit Polyclonal unconjugated

Host: Rabbit Target Name: SLC1A2 Sample Type: Fetal Brain Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/Lane Gel Concentration: 0.

Immunohistochemistry (IHC) image for anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (N-Term) antibody (ABIN2778148)

IHC

Host: Rabbit Target Name: SLC1A2 Sample Type: Fetal Brain lysates Antibody Dilution: 1.

WB Suggested Anti-SLC1A2 Antibody Titration: 0.

Host: Rat Target Name: SLC1A2 Sample Tissue: Rat Brain Antibody Dilution: 1ug/ml

Rabbit Anti-SLC1A2 Antibody Paraffin Embedded Tissue: Human alveolar cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.

IHC

7 images

(1 reference)

Catalog No. ABIN2778148

Datasheet as PDF

Target See all SLC1A2 Antibodies

SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))
Binding Specificity
6

4

4

2

2

2

1

1

1

1

1

1

1

1

1

1

1
N-Term

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Sheep
Host
45

7
Rabbit
Compatible Secondaries
Clonality
45

7
Polyclonal
Conjugate
32

4

4

3

1

1

1

1

1

1

1

1

1
This SLC1A2 antibody is un-conjugated
Application
36

24

20

7

6

5

4

3

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Sequence

PGNPKLKKQL GPGKKNDEVS SLDAFLDLIR NLFPENLVQA CFQQIQTVTK

Predicted Reactivity

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Characteristics

This is a rabbit polyclonal antibody against SLC1A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SLC1A2
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 460-574) antibody
SLC1A2 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 160-239) antibody
SLC1A2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1D8 unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (2nd Extracellular Loop) antibody
SLC1A2 Reactivity: Human, Mouse, Rat WB, IHC, ICC, IF, LCI Host: Rabbit Polyclonal unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 306-348) antibody
SLC1A2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 144-193) antibody
SLC1A2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 467-516) antibody
SLC1A2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (C-Term) antibody
SLC1A2 Reactivity: Human, Mouse WB, IHC, ICC, IHC (p) Host: Mouse Monoclonal unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 1-44) antibody
SLC1A2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (AA 101-200) antibody
SLC1A2 Reactivity: Human, Rat WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated

anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (Internal Region) antibody
SLC1A2 Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilutions should be determined experimentally by the investigator.

Comment

Antigen size: 574 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Pretto, Kumar, Cao, Cunningham, Durbin-Johnson, Qi, Berman, Noctor, Hagerman, Pessah, Tassone et al.: "Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated ..." in: Neurobiology of aging, Vol. 35, Issue 5, pp. 1189-97, (2014) (PubMed).
Target

SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))

Alternative Name

SLC1A2 (SLC1A2 Products)

Synonyms

CG3159 antibody, Dmel\\CG3159 antibody, EAAT antibody, dEAAT2 antibody, dEaat2 antibody, Eaat antibody, GB16377 antibody, EAAT2 antibody, SLC1A2 antibody, Eaat2 antibody, Glt antibody, Glt-1 antibody, GLT-1 antibody, 1700091C19Rik antibody, 2900019G14Rik antibody, AI159670 antibody, GLT1 antibody, MGLT1 antibody, eaat2 antibody, fj34b12 antibody, slc1a2 antibody, wu:fj34b12 antibody, zgc:65897 antibody, Excitatory amino acid transporter 2 antibody, excitatory amino acid transporter 2 antibody, solute carrier family 1 member 2 antibody, solute carrier family 1 (glial high affinity glutamate transporter), member 2 antibody, solute carrier family 1 (glial high affinity glutamate transporter), member 2b antibody, Eaat2 antibody, Eaat-2 antibody, SLC1A2 antibody, VDBG_06180 antibody, EUBELI_01747 antibody, Trebr_0139 antibody, Slc1a2 antibody, slc1a2b antibody

Background

SLC1A2 is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EAAT2, GLT-1
Protein Interaction Partner: PML, GRB2, AJUBA, SLC1A2, MYCN, RELA,
Protein Size: 574

Molecular Weight

62 kDa

Gene ID

6506

NCBI Accession

NM_004171, NP_004162

UniProt

P43004

Pathways

Dicarboxylic Acid Transport