BMP4 antibody
(2 references)-
- Target See all BMP4 Antibodies
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BMP4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody is able to recognize full length BMP4 protein (~55 kDa) and N-terminal propeptide BMP4 protein (~40 kDa) but unable to detect mature form.
- Cross-Reactivity
- Human, Mouse
- Characteristics
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Rabbit Polyclonal antibody to BMP4 (bone morphogenetic protein 4)
BMP4 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human BMP4. The exact sequence is proprietary.
- Isotype
- IgG
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anti-Bone Morphogenetic Protein 4 (BMP4) (C-Term) antibody
BMP4 Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 Reactivity: Human, Rat WB, IHC, ELISA, ICC, FACS Host: Mouse Monoclonal 3C11H8 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 303-408) antibodyBMP4 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 1-408) antibodyBMP4 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 5-34) antibodyBMP4 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 22-408) antibodyBMP4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 23-204) antibodyBMP4 Reactivity: Rabbit WB, IHC, IP, ICC Host: Guinea Pig Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 25-408) antibodyBMP4 Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal PA354-16-1-1 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) antibodyBMP4 Reactivity: Rat, Mouse IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 293-408) antibodyBMP4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: NIH-3T3 , JC , HepG2 conditioned medium
Validation: Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.36 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "TSA restores hair follicle-inductive capacity of skin-derived precursors." in: Scientific reports, Vol. 9, Issue 1, pp. 2867, (2020) (PubMed).
: "Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes." in: Aging, Vol. 11, Issue 23, pp. 11520-11540, (2019) (PubMed).
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: "TSA restores hair follicle-inductive capacity of skin-derived precursors." in: Scientific reports, Vol. 9, Issue 1, pp. 2867, (2020) (PubMed).
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- Target
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
- Alternative Name
- bone morphogenetic protein 4 (BMP4 Products)
- Synonyms
- BMP2B antibody, BMP2B1 antibody, MCOPS6 antibody, OFC11 antibody, ZYME antibody, Bmp-4 antibody, Bmp2b antibody, Bmp2b-1 antibody, Bmp2b1 antibody, BOMPR4A antibody, bmp-4 antibody, zbmp-4 antibody, zgc:100779 antibody, BMP-4 antibody, XBMP-4 antibody, bmp2b antibody, bmp2b1 antibody, bmp4 antibody, ofc11 antibody, xbmp4 antibody, zyme antibody, BMP4 antibody, bone morphogenetic protein 4 antibody, bone morphogenetic protein 4 L homeolog antibody, bone morphogenetic protein 4 S homeolog antibody, BMP4 antibody, Bmp4 antibody, bmp4 antibody, bmp4.L antibody, bmp4.S antibody
- Background
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The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Cellular Localization: Secreted , extracellular space , extracellular matrix - Molecular Weight
- 47 kDa
- Gene ID
- 652
- UniProt
- P12644
- Pathways
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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