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SLC5A5 antibody (AA 525-618)

Name: SLC5A5 antibody (AA 525-618)
SKU: ABIN668751
Price: 384.62 USD
Availability: InStock

SLC5A5 Reactivity: Human, Rat, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-NIS Polyclonal Antibody, Unconjugated (ABIN668751) at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded rat thyroid gland labeled with Anti-NIS Polyclonal Antibody, Unconjugated (ABIN668751) at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded rat thyroid gland labeled with Anti-NIS Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Formalin-fixed and paraffin-embedded human thyroid labeled with Rabbit Anti-NIS Polyclonal Antibody, Unconjugated (ABIN668751) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C.

L1 rat brain lysates L2 rat kidney lysates probed with Anti NIS Polyclonal Antibody, Unconjugated (ABIN668751) at 1:200 overnight at 4 °C.

SDS

5 images

(3 references)

Catalog No. ABIN668751

Datasheet as PDF

Target See all SLC5A5 Antibodies

SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))
Binding Specificity
46

5

3

1

1

1

1

1
AA 525-618
Reactivity
71

32

30

2

2

1
Human, Rat, Pig
Host
52

20
Rabbit
Compatible Secondaries
Clonality
50

20
Polyclonal
Conjugate
25

5

5

5

4

4

4

4

4

4

2

1

1

1

1

1

1
This SLC5A5 antibody is un-conjugated
Application
62

56

22

18

13

11

8

3

3

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Human, Pig, Rat

Predicted Reactivity

Mouse

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from mouse NIS

Isotype

IgG
anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody
SLC5A5 Reactivity: Human WB, IHC, AA Host: Mouse Monoclonal 14F unconjugated

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody
SLC5A5 Reactivity: Human WB, IHC, IF, AA, ICC Host: Mouse Monoclonal FP5 unconjugated

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody (HRP)
SLC5A5 Reactivity: Human WB, IHC, IF, AA, ICC Host: Mouse Monoclonal FP5 HRP

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody (HRP)
SLC5A5 Reactivity: Human WB, IHC, AA Host: Mouse Monoclonal 14F HRP

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody (FITC)
SLC5A5 Reactivity: Human WB, IHC, IF, AA, ICC Host: Mouse Monoclonal FP5 FITC

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody (FITC)
SLC5A5 Reactivity: Human WB, IHC, AA Host: Mouse Monoclonal 14F FITC

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody (Alkaline Phosphatase (AP))
SLC5A5 Reactivity: Human WB, IHC, IF, AA, ICC Host: Mouse Monoclonal FP5 Alkaline Phosphatase (AP)

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody (Alkaline Phosphatase (AP))
SLC5A5 Reactivity: Human WB, IHC, AA Host: Mouse Monoclonal 14F Alkaline Phosphatase (AP)

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody (Biotin)
SLC5A5 Reactivity: Human WB, IHC, IF, AA, ICC Host: Mouse Monoclonal FP5 Biotin

anti-Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5) (AA 468-643) antibody (Biotin)
SLC5A5 Reactivity: Human WB, IHC, AA Host: Mouse Monoclonal 14F Biotin

Application Notes

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Yang, Chen, Guo, Li, Tang, Xu, Sun, Ding, Jiang, Cui, Zheng, Duan: "Molecular Mechanisms of 2, 3', 4, 4', 5-Pentachlorobiphenyl-Induced Thyroid Dysfunction in FRTL-5 Cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120133, (2015) (PubMed).

Guo, Yang, Chen, Li, Tang, Cheng, Xie, Liu, Ding, Cui, Zheng, Duan: "Molecular mechanisms of human thyrocyte dysfunction induced by low concentrations of polychlorinated biphenyl 118 through the Akt/FoxO3a/NIS pathway." in: Journal of applied toxicology : JAT, Vol. 35, Issue 9, pp. 992-8, (2015) (PubMed).

Yao, Pan, Li, Xu, Lin, Wang, Wang: "Effect of sodium/iodide symporter (NIS)-mediated radioiodine therapy on estrogen receptor-negative breast cancer." in: Oncology reports, Vol. 34, Issue 1, pp. 59-66, (2015) (PubMed).
Target

SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Alternative Name

NIS (SLC5A5 Products)

Synonyms

Na(+)/I(-) cotransporter antibody, Na(+)/I(-) symporter antibody, Nis antibody, solute carrier family 5 member 5 antibody, Slc5a5 antibody

Background

Synonyms: Na+/I- cotransporter, Na+/I- symporter, Na+/I- cotransporter, Na+/I- symporter, Na+/I- cotransporter, Na+/I-symporter, NIS, SC5A5_HUMAN, SLC5A5, sodium iodide symporter, Sodium-iodide symporter, Sodium/iodide cotransporter, Solute carrier family 5 sodium iodide symporter member 5, Solute carrier family 5, Solute carrier family 5 member 5.
Background: catalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation.Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.

Gene ID

114479

UniProt

Q99PN0