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SLC6A2 antibody (Middle Region)

SLC6A2 Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777051
  • Target See all SLC6A2 Antibodies
    SLC6A2 (Solute Carrier Family 6 (Neurotransmitter Transporter, Noradrenalin), Member 2 (SLC6A2))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 11
    • 9
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig
    Host
    • 11
    • 1
    Rabbit
    Clonality
    • 11
    • 1
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    This SLC6A2 antibody is un-conjugated
    Application
    • 11
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    STLSGSTFWA VVFFVMLLAL GLDSSMGGME AVITGLADDF QVLKRHRKLF
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SLC6A2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SLC6A2
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 617 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bayles, Harikrishnan, Lambert, Baker, Agrotis, Guo, Jowett, Esler, Lambert, El-Osta: "Epigenetic modification of the norepinephrine transporter gene in postural tachycardia syndrome." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 32, Issue 8, pp. 1910-6, (2012) (PubMed).

    Suzuki, Matsumoto, Oshino, Kamata, Goto, Otani: "Combination of the serotonin transporter and norepinephrine transporter gene promoter polymorphisms might influence harm avoidance and novelty seeking in healthy females." in: Neuroscience letters, Vol. 439, Issue 1, pp. 52-5, (2008) (PubMed).

  • Target
    SLC6A2 (Solute Carrier Family 6 (Neurotransmitter Transporter, Noradrenalin), Member 2 (SLC6A2))
    Alternative Name
    SLC6A2 (SLC6A2 Products)
    Synonyms
    NAT1 antibody, NET antibody, NET1 antibody, SLC6A5 antibody, NE-T antibody, Slc6a5 antibody, Net antibody, SLC6A2 antibody, solute carrier family 6 member 2 antibody, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 antibody, solute carrier family 6 member 5 antibody, SLC6A2 antibody, Slc6a2 antibody, SLC6A5 antibody
    Background
    The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis.The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis (Kim et al., 2006 [PubMed 17146058]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: NAT1, NET, NET1, SLC6A5
    Protein Interaction Partner: SNCA, ACTB, STX1A, PPP2R1A,
    Protein Size: 617
    Molecular Weight
    69 kDa
    Gene ID
    6530
    NCBI Accession
    NM_001043, NP_001034
    UniProt
    P23975
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