SLC12A1 antibody (N-Term)
(3 references)-
- Target See all SLC12A1 Antibodies
- SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
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Binding Specificity
- N-Term
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Reactivity
- Rat, Human, Mouse, Dog, Pig, Rabbit, Guinea Pig, Cow, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC12A1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- NEKKSRGFFN YQASIFAENF GPRFTKGEGF FSVFAIFFPA ATGILAGANI
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SLC12A1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SLC12A1
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anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) antibody
SLC12A1 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibodySLC12A1 Reactivity: Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 52-83), (N-Term) antibodySLC12A1 Reactivity: Rat, Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) antibodySLC12A1 Reactivity: Rat, Mouse IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 80-172) antibodySLC12A1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4H4 unconjugated
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody (HRP)SLC12A1 Reactivity: Rat WB, IHC Host: Rabbit Polyclonal HRP
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody (FITC)SLC12A1 Reactivity: Rat WB, IHC Host: Rabbit Polyclonal FITC
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody (Alkaline Phosphatase (AP))SLC12A1 Reactivity: Rat WB, IHC Host: Rabbit Polyclonal Alkaline Phosphatase (AP)
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 33-55) antibody (Biotin)SLC12A1 Reactivity: Rat WB, IHC Host: Rabbit Polyclonal Biotin
anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (AA 351-400) antibodySLC12A1 Reactivity: Rat, Human, Mouse, Monkey, Dog, Pig, Rabbit, Cow, Horse, Bat WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 430 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Polyuria-associated hydronephrosis induced by xenobiotic chemical exposure in mice." in: American journal of physiology. Renal physiology, Vol. 311, Issue 4, pp. F752-F762, (2016) (PubMed).
: "Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 5, pp. 834-41, (2012) (PubMed).
: "Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells." in: American journal of physiology. Renal physiology, Vol. 295, Issue 4, pp. F1158-65, (2008) (PubMed).
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: "Polyuria-associated hydronephrosis induced by xenobiotic chemical exposure in mice." in: American journal of physiology. Renal physiology, Vol. 311, Issue 4, pp. F752-F762, (2016) (PubMed).
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- Target
- SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
- Alternative Name
- SLC12A1 (SLC12A1 Products)
- Synonyms
- slc12a1 antibody, SLC12A1 antibody, DKFZp469A2020 antibody, BSC1 antibody, NKCC2 antibody, Nkcc2 antibody, AI788571 antibody, D630042G03Rik antibody, mBSC1 antibody, urehr3 antibody, si:ch211-220f12.1 antibody, solute carrier family 12 member 1 antibody, solute carrier family 12, member 1 antibody, si:ch211-220f12.1 antibody, SLC12A1 antibody, Slc12a1 antibody
- Background
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The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle's loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene.
Alias Symbols: BSC1, MGC48843, NKCC2
Protein Interaction Partner: STK39, OXSR1,
Protein Size: 430 - Molecular Weight
- 47 kDa
- Gene ID
- 6557
- NCBI Accession
- NM_000338
- UniProt
- Q8IUN5
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