BMPR2 antibody
(2 references)-
- Target See all BMPR2 Antibodies
- BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
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Reactivity
- Human, Mouse, Rat, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BMPR2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human BMPR2 expressed in E. coli.
- Clone
- 1F12
- Isotype
- IgG1
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anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) antibody
BMPR2 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IHC, ICC Host: Mouse Monoclonal 3F6 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 28-59) antibodyBMPR2 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 28-59) antibodyBMPR2 Reactivity: Human, Mouse WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 28-59), (N-Term) antibodyBMPR2 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB01778 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) antibodyBMPR2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-150) antibodyBMPR2 Reactivity: Human WB, ELISA, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (Internal Region) antibodyBMPR2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-56), (N-Term) antibodyBMPR2 Reactivity: Human, Mouse IHC (p), FACS Host: Rabbit Polyclonal RB1806 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (C-Term) antibodyKO Validated BMPR2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-56) antibodyBMPR2 Reactivity: Human, Mouse ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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: "Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension." in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, Vol. 27, Issue 6, pp. 668-74, (2008) (PubMed).
: "Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension." in: Genetics in medicine : official journal of the American College of Medical Genetics, Vol. 10, Issue 5, pp. 359-65, (2008) (PubMed).
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: "Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension." in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, Vol. 27, Issue 6, pp. 668-74, (2008) (PubMed).
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- Target
- BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
- Alternative Name
- BMPR2 (BMPR2 Products)
- Synonyms
- BMPR-II antibody, BMPR3 antibody, BMR2 antibody, BRK-3 antibody, PPH1 antibody, T-ALK antibody, 2610024H22Rik antibody, AL117858 antibody, AW546137 antibody, BB189135 antibody, BMP-2 antibody, BMPR-2 antibody, BMPRII antibody, Gm20272 antibody, Bmpr-II antibody, bmprii antibody, bone morphogenetic protein receptor type 2 antibody, bone morphogenetic protein receptor, type II b (serine/threonine kinase) antibody, bone morphogenetic protein receptor, type II (serine/threonine kinase) antibody, BMPR2 antibody, bmpr2b antibody, Bmpr2 antibody
- Background
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Description: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. (provided by RefSeq)
Aliases: BMR2, PPH1, BMPR3, BRK-3, T-ALK, BMPR-II, FLJ41585, FLJ76945, BMPR2
- Molecular Weight
- 115 kDa
- Gene ID
- 659
- HGNC
- 659
- Pathways
- Growth Factor Binding
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