SLPI Protein (AA 26-132) (Fc Tag)
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- Target See all SLPI Proteins
- SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-132
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SLPI protein is labelled with Fc Tag.
- Purpose
- Human SLPI Protein
- Sequence
- Ser26-Ala132
- Characteristics
- Recombinant Human SLPI Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser26-Ala132.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human SLPI, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-SLPI Antibody, hFc Tag with the EC50 of 0.47μg/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS, 350 mM NaCl ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
- Alternative Name
- SLPI (SLPI Products)
- Synonyms
- ALK1 Protein, ALP Protein, BLPI Protein, HUSI Protein, HUSI-I Protein, MPI Protein, WAP4 Protein, WFDC4 Protein, MATN4 Protein, SLPI Protein, ckpi Protein, secretory leukocyte peptidase inhibitor Protein, antileukoproteinase Protein, SLPI Protein, Slpi Protein, LOC102174044 Protein
- Background
- Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation of the response to LPS (lipopolysaccharide) stimulation. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions.
- Molecular Weight
- 38.5 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
- UniProt
- P03973
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