U2 Small Nuclear Ribonucleoprotein B'' (SNRPB2) (N-Term) antibody
-
- Target
- U2 Small Nuclear Ribonucleoprotein B'' (SNRPB2)
- Binding Specificity
- N-Term
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SNRPB2. The exact sequence is proprietary.
- Isotype
- IgG
-
- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
-
Positive Control: U87-MG nuclear extract , HepG2 nuclear extract Validation: Orthogonal
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Target
- U2 Small Nuclear Ribonucleoprotein B'' (SNRPB2)
- Alternative Name
- small nuclear ribonucleoprotein polypeptide B2
- Synonyms
- Msl1 antibody, small nuclear ribonucleoprotein polypeptide B2 antibody, SNRPB2 antibody
- Background
-
Synonyms: small nuclear ribonucleoprotein polypeptide B2 , Msl1 , U2B''
Background: The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
- Molecular Weight
- 25 kDa
- Gene ID
- 6629
- UniProt
- P08579
-