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SOS1 antibody (AA 1140-1281)

SOS1 Reactivity: Human WB, ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7170318
  • Target See all SOS1 Antibodies
    SOS1 (Son of Sevenless Homolog 1 (SOS1))
    Binding Specificity
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1140-1281
    Reactivity
    • 25
    • 11
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 17
    • 10
    • 1
    Rabbit
    Clonality
    • 18
    • 10
    Polyclonal
    Conjugate
    • 25
    • 1
    • 1
    • 1
    This SOS1 antibody is un-conjugated
    Application
    • 20
    • 13
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    Cross-Reactivity
    Human, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Son of sevenless homolog 1 protein (1140-1281AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SOS1 (Son of Sevenless Homolog 1 (SOS1))
    Alternative Name
    SOS1 (SOS1 Products)
    Synonyms
    GF1 antibody, GGF1 antibody, GINGF antibody, HGF antibody, NS4 antibody, 4430401P03Rik antibody, 9630010N06 antibody, AI449023 antibody, SOS Ras/Rac guanine nucleotide exchange factor 1 antibody, son of sevenless homolog 1 (Drosophila) antibody, SOS1 antibody, Sos1 antibody
    Target Type
    Viral Protein
    Background

    Background: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).

    Aliases: alternate SOS1 antibody, GF1 antibody, GGF1 antibody, GINGF antibody, gingival fibromatosis antibody, gingival fibromatosis hereditary 1 antibody, Guanine nucleotide exchange factor antibody, HGF antibody, NS4 antibody, Son of sevenless homolog 1 (Drosophila) antibody, Son of sevenless homolog 1 antibody, SOS Ras/Rac guanine nucleotide exchange factor 1 antibody, SOS-1 antibody, Sos1 antibody, SOS1_HUMAN antibody

    UniProt
    Q07889
    Pathways
    RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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