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SPINK1 antibody (AA 24-79)

SPINK1 Reactivity: Human WB, ELISA, IHC (p), IP Host: Mouse Monoclonal 4D4 unconjugated
Catalog No. ABIN562978
  • Target See all SPINK1 Antibodies
    SPINK1 (serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))
    Binding Specificity
    • 15
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 24-79
    Reactivity
    • 35
    • 16
    • 2
    • 1
    • 1
    Human
    Host
    • 45
    • 4
    • 1
    Mouse
    Clonality
    • 46
    • 4
    Monoclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SPINK1 antibody is un-conjugated
    Application
    • 26
    • 26
    • 14
    • 12
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant SPINK1.
    Sequence
    DSLGREAKCY NELNGCTKIY DPVCGTDGNT YPNECVLCFE NRKRQTSILI QKSGPC
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    SPINK1 (AAH25790, 24 a.a. ~ 79 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    4D4
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Palanisamy, Tsodikov, Yan, Suleman, Rittmaster, Lucia, Chinnaiyan, Fleshner, Kunju: "Molecular profiling of ETS gene rearrangements in patients with prostate cancer registered in REDEEM clinical trial." in: Urologic oncology, Vol. 33, Issue 3, pp. 108.e5-108.e13, (2015) (PubMed).

    Ateeq, Kunju, Carskadon, Pandey, Singh, Pradeep, Tandon, Singhai, Goel, Amit, Agarwal, Dinda, Seth, Tsodikov, Chinnaiyan, Palanisamy: "Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India." in: The Prostate, Vol. 75, Issue 10, pp. 1051-62, (2015) (PubMed).

    Zhang, Wang, Hu, Wang, Yu, Wang: "The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line." in: Tumour biology, (2015) (PubMed).

    Smith, Palanisamy, Zuhlke, Johnson, Siddiqui, Chinnaiyan, Kunju, Cooney, Tomlins: "HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey." in: The American journal of surgical pathology, Vol. 38, Issue 5, pp. 615-26, (2014) (PubMed).

    Rink, Park, Volkmer, Xylinas, Hansen, Cha, Robinson, Hautmann, Küfer, Engel, Chun, Dahlem, Rubin, Shariat, Mosquera: "Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy." in: Urologic oncology, Vol. 31, Issue 8, pp. 1716-24, (2013) (PubMed).

    Bhalla, Kunju, Tomlins, Christopherson, Cortez, Carskadon, Siddiqui, Park, Mosquera, Pestano, Rubin, Chinnaiyan, Palanisamy: "Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 6, pp. 835-48, (2013) (PubMed).

    Han, Mehra, Suleman, Tomlins, Wang, Singhal, Linetzky, Palanisamy, Zhou, Chinnaiyan, Shah: "Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 9, pp. 1176-85, (2009) (PubMed).

    Tomlins, Rhodes, Yu, Varambally, Mehra, Perner, Demichelis, Helgeson, Laxman, Morris, Cao, Cao, Andrén, Fall, Johnson, Wei, Shah, Al-Ahmadie, Eastham, Eggener, Fine, Hotakainen, Stenman, Tsodikov et al.: "The role of SPINK1 in ETS rearrangement-negative prostate cancers. ..." in: Cancer cell, Vol. 13, Issue 6, pp. 519-28, (2008) (PubMed).

  • Target
    SPINK1 (serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))
    Alternative Name
    SPINK1 (SPINK1 Products)
    Synonyms
    PCTT antibody, PSTI antibody, Spink3 antibody, TATI antibody, TCP antibody, Psti antibody, SPINK1 antibody, p12 antibody, serine peptidase inhibitor, Kazal type 1 antibody, SPINK1 antibody, Spink1 antibody
    Background
    Full Gene Name: serine peptidase inhibitor, Kazal type 1
    Synonyms: PCTT,PSTI,Spink3,TATI
    Gene ID
    6690
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