POLR3D antibody (Internal Region)
-
- Target See all POLR3D Antibodies
- POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))
-
Binding Specificity
- Internal Region
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This POLR3D antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- RPC4 Antibody detects endogenous levels of total RPC4.
- Predicted Reactivity
- Pig,Bovine,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RPC4, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product POLR3D Primary Antibody
-
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (AA 1-398) antibody
POLR3D Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) antibodyPOLR3D Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (AA 127-156) antibodyPOLR3D Reactivity: Human WB Host: Rabbit Polyclonal RB33419 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (AA 296-395) antibodyPOLR3D Reactivity: Human ELISA Host: Mouse Monoclonal 4E6 unconjugated
-
- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
-
- Target
- POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))
- Alternative Name
- POLR3D (POLR3D Products)
- Synonyms
- 2810426M17Rik antibody, 44kDa antibody, AI326118 antibody, AW489084 antibody, BN51T antibody, RPC4 antibody, TSBN51 antibody, RPC53 antibody, RNA polymerase III subunit D antibody, polymerase (RNA) III (DNA directed) polypeptide D antibody, Polr3d antibody, POLR3D antibody
- Background
-
Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Gene: POLR3D
- Molecular Weight
- 38 kDa
- Gene ID
- 661
- UniProt
- P05423
-
