SPTAN1 antibody (AA 950-1130)
(1 reference)-
- Target See all SPTAN1 Antibodies
- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
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Binding Specificity
- AA 950-1130
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPTAN1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- REQAQSCRQQ VAPTDDETGK ELVLALYDYQ EKSPREVTMK KGDILTLLNS TNKDWWKVEV NDRQGFVPAA YVKKLDPAQS ASRENLLEEQ GSIALRQEQI DNQTRITKEA GSVSLRMKQV EELYHSLLEL GEKRKGMLEK SCKKFMLFRE ANELQQWINE KEAALTSEEV GADLEQVEVL Q
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 950-1130 of human Alpha Fodrin (NP_001123910.1).
- Isotype
- IgG
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anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 2071-2269) antibody
SPTAN1 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) antibodySPTAN1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 1573-1742) antibodySPTAN1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) antibodySPTAN1 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 2351-2475) antibodySPTAN1 Reactivity: Human IHC, StM Host: Mouse Monoclonal SPTAN1-3351 unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 289-408) antibodySPTAN1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 977-991) antibodySPTAN1 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal RB50708 unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 2351-2475) antibodySPTAN1 Reactivity: Human IHC, ELISA, Coat Host: Mouse Monoclonal SPTAN1-3352 unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 1004-1181) antibodySPTAN1 Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (Cleaved-Asp1185) antibodySPTAN1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis." in: Neuroscience, Vol. 307, pp. 160-70, (2016) (PubMed).
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: "Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis." in: Neuroscience, Vol. 307, pp. 160-70, (2016) (PubMed).
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- Target
- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
- Alternative Name
- SPTAN1 (SPTAN1 Products)
- Synonyms
- im:7157190 antibody, wu:fa20e05 antibody, wu:fb33g08 antibody, wu:fk32a10 antibody, zgc:112229 antibody, 2610027H02Rik antibody, Spna-2 antibody, Spna2 antibody, EIEE5 antibody, NEAS antibody, SPTA2 antibody, A2a antibody, IPF antibody, SPECA antibody, spectrin alpha, non-erythrocytic 1 antibody, spectrin, alpha, non-erythrocytic 1 antibody, SPTAN1 antibody, sptan1 antibody, Sptan1 antibody
- Background
- Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.,SPTAN1,EIEE5,NEAS,SPTA2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Death Receptor Signaling Pathway,SPTAN1
- Molecular Weight
- 282 kDa/284 kDa/285 kDa
- Gene ID
- 6709
- UniProt
- Q13813
- Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
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