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RNLS antibody (C-Term)

RNLS Reactivity: Human, Mouse, Rat WB, IHC, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264793
  • Target See all RNLS Antibodies
    RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
    Binding Specificity
    • 15
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 41
    • 25
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 7
    • 1
    Rabbit
    Clonality
    • 41
    • 7
    Polyclonal
    Conjugate
    • 23
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNLS antibody is un-conjugated
    Application
    • 39
    • 18
    • 13
    • 13
    • 13
    • 9
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    RNLS Antibody detects endogenous levels of total RNLS.
    Predicted Reactivity
    Pig,Horse,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RNLS, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RNLS Primary Antibody
  • Application Notes
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
    Alternative Name
    RNLS (RNLS Products)
    Synonyms
    zgc:92286 antibody, C10orf59 antibody, RENALASE antibody, 6530404N21Rik antibody, AI452315 antibody, AW060440 antibody, RGD1309804 antibody, renalase, FAD dependent amine oxidase antibody, renalase, FAD-dependent amine oxidase antibody, RNLS antibody, rnls antibody, Rnls antibody
    Background

    Description: Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

    Gene: RNLS

    Molecular Weight
    38 kDa
    Gene ID
    55328
    UniProt
    Q5VYX0
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