CAMSAP2 antibody (C-Term)
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- Target See all CAMSAP2 (CAMSAP1L1) products
- CAMSAP2 (CAMSAP1L1) (Calmodulin Regulated Spectrin-associated Protein 1-like 1 (CAMSAP1L1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CAMSAP2 antibody is un-conjugated
- Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- CAMSAP2 Antibody detects endogenous levels of total CAMSAP2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CAMSAP2, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
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anti-Calmodulin Regulated Spectrin-associated Protein 1-like 1 (CAMSAP1L1) (AA 1-150) antibody
CAMSAP1L1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- CAMSAP2 (CAMSAP1L1) (Calmodulin Regulated Spectrin-associated Protein 1-like 1 (CAMSAP1L1))
- Alternative Name
- CAMSAP2 (CAMSAP1L1 Products)
- Synonyms
- Camsap1l1 antibody, RGD1310950 antibody, camsap1l1 antibody, si:dkey-39e8.1 antibody, wu:fc16g04 antibody, wu:fc23h08 antibody, CAMSAP1L1 antibody, 1600013L13Rik antibody, 4930541M15Rik antibody, mKIAA1078 antibody, calmodulin regulated spectrin-associated protein family, member 2 antibody, calmodulin regulated spectrin associated protein family member 2 antibody, calmodulin regulated spectrin-associated protein family, member 2a antibody, Camsap2 antibody, CAMSAP2 antibody, camsap2a antibody, camsap2 antibody
- Background
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Description: Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:23169647, PubMed:24486153, PubMed:24706919). Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization (PubMed:24486153, PubMed:24706919). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (PubMed:24486153, PubMed:24706919). In addition, it also reduces the velocity of microtubule polymerization (PubMed:24486153, PubMed:24706919). Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes (PubMed:27666745). Essential for the tethering, but not for nucleation of non-centrosomal microtubules at the Golgi: together with Golgi-associated proteins AKAP9 and PDE4DIP, required to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745). Also acts as a regulator of neuronal polarity and development: localizes to non-centrosomal microtubule minus-ends in neurons and stabilizes non-centrosomal microtubules, which is required for neuronal polarity, axon specification and dendritic branch formation (PubMed:24908486). Through the microtubule cytoskeleton, regulates the autophagosome transport (PubMed:28726242).
Gene: CAMSAP2
- Molecular Weight
- 168 kDa
- Gene ID
- 23271
- UniProt
- Q08AD1
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