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AREL1 antibody (N-Term)

AREL1 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782048
  • Target See all AREL1 products
    AREL1 (Apoptosis Resistant E3 Ubiquitin Protein Ligase 1 (AREL1))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 6
    • 1
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 7
    This AREL1 antibody is un-conjugated
    Application
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    LTCGQPHTLQ IVPRDEYDNP TNNSMSLRDE HNYTLSIHEL GPQEEESTGV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against KIAA0317. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human KIAA0317
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 823 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lear, McKelvey, Rajbhandari, Dunn, Coon, Connelly, Zhao, Kass, Zhang, Liu, Chen: "Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4." in: The Journal of experimental medicine, Vol. 213, Issue 6, pp. 1029-46, (2016) (PubMed).

  • Target
    AREL1 (Apoptosis Resistant E3 Ubiquitin Protein Ligase 1 (AREL1))
    Alternative Name
    KIAA0317 (AREL1 Products)
    Synonyms
    KIAA0317 antibody, apoptosis resistant E3 ubiquitin protein ligase 1 antibody, AREL1 antibody
    Background
    KIAA0317 contains 1 filamin repeat and 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. The exact function of KIAA0317 remains unknown.
    Alias Symbols: KIAA0317,
    Protein Interaction Partner: UBC, Htra2, DIABLO, AREL1, UBE2D1, SEPT4, HSP90AA1,
    Protein Size: 823
    Molecular Weight
    94 kDa
    Gene ID
    9870
    NCBI Accession
    NM_001039479, NP_001034568
    UniProt
    O15033
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