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ADAM17 antibody (AA 226-473)

ADAM17 Reactivity: Human WB, IHC, ICC, IP Host: Mouse Monoclonal C10 unconjugated
Catalog No. ABIN7426310
  • Target See all ADAM17 Antibodies
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Binding Specificity
    • 16
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 226-473
    Reactivity
    • 114
    • 54
    • 52
    • 4
    • 4
    • 4
    • 1
    • 1
    Human
    Host
    • 100
    • 12
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 92
    • 24
    Monoclonal
    Conjugate
    • 53
    • 11
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM17 antibody is un-conjugated
    Application
    • 86
    • 53
    • 40
    • 15
    • 14
    • 13
    • 12
    • 11
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Purpose
    Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17)
    Specificity
    The antibody is a mouse monoclonal antibody raised against ADAM17. It has been selected for its ability to recognize ADAM17 in immunohistochemical staining and western blotting.
    Cross-Reactivity
    Mouse, Rat
    Purification
    Protein A + Protein G affinity chromatography
    Immunogen
    Recombinant A Disintegrin And Metalloprotease 17 (ADAM17) corresdonding to Lys226~Arg473 with N-terminal His Tag
    Clone
    C10
    Isotype
    IgG1 kappa
  • Application Notes

    Western blotting: 0.5-2 μg/mL

    1:500-2000 Immunohistochemistry: 5-20 μg/mL

    1:50-200 Immunocytochemistry: 5-20 μg/mL

    1:50-200 Optimal working dilutions must be determined by end user.

    Comment

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
    Expiry Date
    24 months
  • Target
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Alternative Name
    A Disintegrin And Metalloprotease 17 (ADAM17 Products)
    Synonyms
    ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody
    Background
    CD156b, TACE, CSVP, Tumor Necrosis Factor,Alpha,Converting Enzyme, Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease
    Pathways
    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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