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ASCC1 antibody

ASCC1 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7240817
  • Target See all ASCC1 Antibodies
    ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))
    Reactivity
    • 21
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 19
    • 2
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASCC1 antibody is un-conjugated
    Application
    • 11
    • 7
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human ASCC1
    Isotype
    IgG
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  • Application Notes
    IHC 1:25-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.3 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))
    Alternative Name
    ASCC1 (ASCC1 Products)
    Synonyms
    ASC1p50 antibody, p50 antibody, Asc-1 antibody, CGI-18 antibody, 1810015P09Rik antibody, AI550520 antibody, activating signal cointegrator 1 complex subunit 1 antibody, ascc1 antibody, ASCC1 antibody, Ascc1 antibody
    Background
    This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
    UniProt
    Q8N9N2
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