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CDK12 antibody

CRKRS Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7001259
  • Target See all CDK12 (CRKRS) Antibodies
    CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
    Reactivity
    • 36
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 33
    • 3
    Rabbit
    Clonality
    • 33
    • 3
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK12 antibody is un-conjugated
    Application
    • 23
    • 21
    • 3
    • 2
    • 2
    • 2
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human CDK12
    Isotype
    IgG
    Top Product
    Discover our top product CRKRS Primary Antibody
  • Application Notes
    IHC 1:25-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
    Alternative Name
    CDK12 (CRKRS Products)
    Synonyms
    AC017581 antibody, CG7597 antibody, Dmel\\CG7597 antibody, anon-WO0140519.165 antibody, cg7597 antibody, dCDK12 antibody, gi24668141 antibody, CRK7 antibody, CRKR antibody, CRKRS antibody, hCDK12 antibody, 1810022J16Rik antibody, AI646528 antibody, Crk7 antibody, Crkrs antibody, D11Ertd752e antibody, Pksc antibody, Cyclin-dependent kinase 12 antibody, cyclin dependent kinase 12 antibody, cyclin-dependent kinase 12 antibody, Cdk12 antibody, CDK12 antibody
    Background
    CrkRS (Cdc2-related kinase, arginine/serine-rich, also designated CRK7 and CRKR) is an ubiquitous protein that appears to localize to the nucleus and link transcription and splicing machinery. CrkRS belongs to the serine/threonine protein kinase family and Cdc2/Cdkx subfamily. CrkRS has extensive proline-rich regions that resemble SH3 and WW domain binding sites, and an RS domain that is characteristic of splicing factors. The protein kinase domain of CrkRS is 89 % identical to the CHED protein kinase, also designated CDC2L5 and cell division cycle 2-like 5 (cholinesterase-related cell division controller), however outside the kinase domains the two proteins are unique. Cell cycle control kinases can phosphorylate proteins important for differentiation and apoptosis and provide connections between proliferation, differentiation, apoptosis, and neurocytoskeleton dynamics.
    NCBI Accession
    NP_057591
    UniProt
    Q9NYV4
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