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BTK antibody (AA 30-240)

BTK Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3022171
  • Target See all BTK Antibodies
    BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
    Binding Specificity
    • 44
    • 22
    • 16
    • 15
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-240
    Reactivity
    • 147
    • 90
    • 79
    • 14
    • 6
    • 4
    • 2
    Human
    Host
    • 169
    • 9
    Rabbit
    Clonality
    • 144
    • 35
    Polyclonal
    Conjugate
    • 69
    • 15
    • 12
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This BTK antibody is un-conjugated
    Application
    • 107
    • 67
    • 40
    • 40
    • 36
    • 27
    • 18
    • 16
    • 11
    • 10
    • 9
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    FLLTVHKLSY YEYDFERGRR GSKKGSIDVE KITCVETVVP EKNPPPERQI PRRGEESSEM EQISIIERFP YPFQVVYDEG PLYVFSPTEE LRKRWIHQLK NVIRYNSDLV QKYHPCFWID GQYLCCSQTA KNAMGCQILE NRNGSLKPGS SHRKTKKPLP PTPEEDQILK KPLPPEPAAA PVSTSELKKV VALYDYMPMN ANDLQLRKGD E
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human BTK (NP_000052.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
    Alternative Name
    BTK (BTK Products)
    Synonyms
    BTK antibody, atk antibody, bpk antibody, xla antibody, imd1 antibody, agmx1 antibody, psctk1 antibody, AGMX1 antibody, AT antibody, ATK antibody, BPK antibody, IMD1 antibody, PSCTK1 antibody, XLA antibody, AI528679 antibody, xid antibody, Bruton tyrosine kinase antibody, Bruton agammaglobulinemia tyrosine kinase antibody, BTK antibody, btk antibody, Btk antibody
    Background
    The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.,AGMX1,AT,ATK,BPK,IMD1,PSCTK1,XLA,BTK,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,BTK
    Molecular Weight
    76 kDa/79 kDa
    Gene ID
    695
    UniProt
    Q06187
    Pathways
    Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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