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MZB1 antibody

MZB1 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7257892
  • Target See all MZB1 Antibodies
    MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))
    Reactivity
    Human, Mouse, Rat
    Host
    • 10
    • 1
    Rabbit
    Clonality
    • 11
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    This MZB1 antibody is un-conjugated
    Application
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MZB1 (NP_057543.2).
    Isotype
    IgG
    Top Product
    Discover our top product MZB1 Primary Antibody
  • Application Notes
    IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))
    Alternative Name
    MZB1 (MZB1 Products)
    Synonyms
    PACAP antibody, pERp1 antibody, MEDA-7 antibody, Pacap antibody, RGD1310251 antibody, 2010001M09Rik antibody, AV064572 antibody, marginal zone B and B1 cell specific protein antibody, marginal zone B and B1 cell-specific protein antibody, marginal zone B and B1 cell-specific protein 1 antibody, MZB1 antibody, Mzb1 antibody
    Background
    Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
    Gene ID
    51237
    UniProt
    Q8WU39
    Pathways
    Production of Molecular Mediator of Immune Response
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