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PAK4 antibody (AA 187-216)

PAK4 Reactivity: Human, Mouse WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032118
  • Target See all PAK4 Antibodies
    PAK4 (P21-Activated Kinase 4 (PAK4))
    Binding Specificity
    • 14
    • 11
    • 8
    • 8
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 187-216
    Reactivity
    • 91
    • 54
    • 36
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 85
    • 5
    • 1
    Rabbit
    Clonality
    • 85
    • 6
    Polyclonal
    Conjugate
    • 42
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAK4 antibody is un-conjugated
    Application
    • 75
    • 42
    • 24
    • 19
    • 9
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 187-216 from the mouse protein was used as the immunogen for this Pak4 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PAK4 Primary Antibody
  • Application Notes
    Titration of the Pak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Pak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PAK4 (P21-Activated Kinase 4 (PAK4))
    Alternative Name
    Pak4 (PAK4 Products)
    Synonyms
    5730488L07Rik antibody, AW555722 antibody, mKIAA1142 antibody, im:5916170 antibody, wu:fd12b01 antibody, zgc:92014 antibody, p21 (RAC1) activated kinase 4 antibody, p21 protein (Cdc42/Rac)-activated kinase 4 antibody, PAK4 antibody, Pak4 antibody, pak4 antibody
    Background
    Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).
    UniProt
    Q8BTW9
    Pathways
    RTK Signaling
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