SFPQ antibody
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- Target See all SFPQ Antibodies
- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SFPQ antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human SFPQ (NP_005057.1).
- Isotype
- IgG
- Top Product
- Discover our top product SFPQ Primary Antibody
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anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 269-361) antibody
SFPQ Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 6D7 unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 578-707) antibodySFPQ Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) antibodySFPQ Reactivity: Human IHC, IF Host: Rabbit Monoclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (N-Term) antibodySFPQ Reactivity: Human, Mouse, Rat, Cow, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (C-Term) antibodySFPQ Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 191-240) antibodySFPQ Reactivity: Human, Mouse, Rat, Cow, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 444-493) antibodySFPQ Reactivity: Human, Mouse, Rat, Cow, Chicken, Horse, Guinea Pig, Rabbit, Monkey, Bat WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 269-362) antibodySFPQ Reactivity: Human WB, ELISA, IHC, IF, IHC (p) Host: Mouse Monoclonal 6D7 unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (Middle Region) antibodySFPQ Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 499-598) antibodySFPQ Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
- Alternative Name
- SFPQ (SFPQ Products)
- Synonyms
- 1110004P21Rik antibody, 2810416M14Rik antibody, 5730453G22Rik antibody, 9030402K04Rik antibody, AU021830 antibody, D4Ertd314e antibody, Gm12940 antibody, OTTMUSG00000009329 antibody, PSF antibody, REP1 antibody, hm:zeh0027 antibody, wu:fa11h12 antibody, wu:fd10f03 antibody, zgc:85935 antibody, POMP100 antibody, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) antibody, splicing factor proline/glutamine-rich antibody, splicing factor proline and glutamine rich antibody, Sfpq antibody, sfpq antibody, SFPQ antibody
- Background
- DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45, a phosphorylated form is sequestered by THRAP3 from the pre-mRNA in resting T-cells, T-cell activation and subsequent reduced phosphorylation is proposed to lead to release from THRAP3 allowing binding to pre-mRNA splicing regulatotry elements which represses exon inclusion. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A.
- Molecular Weight
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Observed_MW: 115 kDa
Calculated_MW: 72 kDa/76 kDa
- Gene ID
- 6421
- UniProt
- P23246
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