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Thyroperoxidase antibody (AA 351-450)

TPO Reactivity: Human, Rat WB, IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN668736
  • Target See all Thyroperoxidase (TPO) Antibodies
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Binding Specificity
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivity
    • 57
    • 24
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 39
    • 26
    • 3
    Rabbit
    Clonality
    • 45
    • 22
    Polyclonal
    Conjugate
    • 29
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Thyroperoxidase antibody is un-conjugated
    Application
    • 51
    • 29
    • 13
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Thyroid peroxidase
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Alternative Name
    Thyroid peroxidase (TPO Products)
    Synonyms
    MSA antibody, TDH2A antibody, TPX antibody, TPO antibody, msa antibody, tpx antibody, xtpo antibody, LOC100218312 antibody, thyroid peroxidase antibody, TPO antibody, Tpo antibody, tpo antibody, LOC100547103 antibody
    Background

    Synonyms: Thyroid peroxidase, TPO

    Background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].

    Gene ID
    22018
    UniProt
    P35419
    Pathways
    Thyroid Hormone Synthesis
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