TRAF2 antibody (AA 1-300)
(1 reference)-
- Target See all TRAF2 Antibodies
- TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))
-
Binding Specificity
- AA 1-300
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TRAF2 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Sequence
- MAAASVTPPG SLELLQPGFS KTLLGTKLEA KYLCSACRNV LRRPFQAQCG HRYCSFCLAS ILSSGPQNCA ACVHEGIYEE GISILESSSA FPDNAARREV ESLPAVCPSD GCTWKGTLKE YESCHEGRCP LMLTECPACK GLVRLGEKER HLEHECPERS LSCRHCRAPC CGADVKAHHE VCPKFPLTCD GCGKKKIPRE KFQDHVKTCG KCRVPCRFHA IGCLETVEGE KQQEHEVQWL REHLAMLLSS VLEAKPLLGD QSHAGSELLQ RCESLEKKTA TFENIVCVLN REVERVAMTA
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRAF2 (NP_066961.2).
- Isotype
- IgG
-
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 238-491) antibody
TRAF2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyVerified TRAF2 Reactivity: Human, Mouse WB, ELISA, IHC, IF, FACS Host: Goat Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 39-188) antibodyTRAF2 Reactivity: Human WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 5C2C3 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) antibodyTRAF2 Reactivity: Human WB, ELISA, IHC, IP, FACS Host: Rabbit Monoclonal 9A5 unconjugated Recombinant Antibody
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 39-188) antibodyTRAF2 Reactivity: Human WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 4A12D9 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 147-281) antibodyTRAF2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 401-501) antibodyTRAF2 Reactivity: Human WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyTRAF2 Reactivity: Human, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 1-501) antibodyTRAF2 Reactivity: Human WB, ELISA, PLA Host: Mouse Monoclonal 4C11 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyTRAF2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
: "Combination of arsenic trioxide and Dasatinib: a new strategy to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1614-1626, (2018) (PubMed).
-
: "Combination of arsenic trioxide and Dasatinib: a new strategy to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1614-1626, (2018) (PubMed).
-
- Target
- TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))
- Alternative Name
- TRAF2 (TRAF2 Products)
- Synonyms
- MGC:45012 antibody, TRAP antibody, TRAP3 antibody, TANK antibody, AI325259 antibody, TNF-receptor-associated factor 2 antibody, conjugal transfer protein TraF antibody, TNF receptor associated factor 2 antibody, TNF receptor-associated factor 2 antibody, Tnf receptor-associated factor 2 antibody, LOC661716 antibody, traF2 antibody, TRAF2 antibody, Traf2 antibody
- Background
- The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.,MGC:45012,TRAP,TRAP3,TRAF2,Cancer,Signal Transduction,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Autophagy,Growth factor,TNF,Death Receptor Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Cardiovascular,TRAF2
- Molecular Weight
- 53 kDa/54 kDa/55 kDa/61 kDa
- Gene ID
- 7186
- UniProt
- Q12933
- Pathways
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response, S100 Proteins
-
