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DDX42 antibody (C-Term)

DDX42 Reactivity: Human, Mouse WB, ELISA, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261256
  • Target See all DDX42 Antibodies
    DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))
    Binding Specificity
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 21
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 19
    • 2
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDX42 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Specificity
    DDX42 Antibody detects endogenous levels of total DDX42.
    Predicted Reactivity
    Pig,Bovine,Horse,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human DDX42, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product DDX42 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))
    Alternative Name
    DDX42 (DDX42 Products)
    Synonyms
    im:7148194 antibody, si:dkey-15n1.10 antibody, zgc:111815 antibody, DDX42P antibody, RHELP antibody, RNAHP antibody, SF3b125 antibody, 1810047H21Rik antibody, AW319508 antibody, AW556242 antibody, B430002H05Rik antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 42 antibody, DEAD-box helicase 42 antibody, DEAD-box helicase 42 L homeolog antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 antibody, ddx42 antibody, DDX42 antibody, Ddx42 antibody, ddx42.L antibody
    Background

    Description: ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

    Gene: DDX42

    Molecular Weight
    103 kDa
    Gene ID
    11325
    UniProt
    Q86XP3
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