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TSH receptor antibody (AA 21-253)

TSHR Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6149622
  • Target See all TSH receptor (TSHR) Antibodies
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Binding Specificity
    • 16
    • 16
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-253
    Reactivity
    • 78
    • 54
    • 35
    • 9
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Host
    • 66
    • 15
    • 1
    • 1
    Rabbit
    Clonality
    • 67
    • 16
    Polyclonal
    Conjugate
    • 44
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSH receptor antibody is un-conjugated
    Application
    • 44
    • 42
    • 20
    • 15
    • 13
    • 13
    • 13
    • 9
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    GMGCSSPPCE CHQEEDFRVT CKDIQRIPSL PPSTQTLKLI ETHLRTIPSH AFSNLPNISR IYVSIDVTLQ QLESHSFYNL SKVTHIEIRN TRNLTYIDPD ALKELPLLKF LGIFNTGLKM FPDLTKVYST DIFFILEITD NPYMTSIPVN AFQGLCNETL TLKLYNNGFT SVQGYAFNGT KLDAVYLNKN KYLTVIDKDA FGGVYSGPSL LLPLGRKSLS FETQKAPRSS MPS
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 21-253 of human TSHR (NP_001018046.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Yang, Yi, Zhang, He, He, Wu, Xu, Li, Fan, Zhu, Xue, Zhou: "Generation and characterization of a hypothyroidism rat model with truncated thyroid stimulating hormone receptor." in: Scientific reports, Vol. 8, Issue 1, pp. 4004, (2018) (PubMed).

  • Target
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Alternative Name
    TSHR (TSHR Products)
    Synonyms
    CHNG1 antibody, LGR3 antibody, hTSHR-I antibody, AI481368 antibody, hypothroid antibody, hyt antibody, pet antibody, TSHRA antibody, TSH-R antibody, thyroid stimulating hormone receptor antibody, tshr antibody, TSHR antibody, Tshr antibody
    Background
    The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.,TSHR,CHNG1,LGR3,hTSHR-I,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,TSHR
    Molecular Weight
    28 kDa/30 kDa/86 kDa
    Gene ID
    7253
    UniProt
    P16473
    Pathways
    Thyroid Hormone Synthesis
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