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TYR antibody

TYR Reactivity: Human, Mouse, Rat WB, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7256196
  • Target See all TYR Antibodies
    TYR (Tyrosinase (TYR))
    Reactivity
    • 90
    • 22
    • 19
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 54
    • 37
    Rabbit
    Clonality
    • 47
    • 45
    Polyclonal
    Conjugate
    • 53
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TYR antibody is un-conjugated
    Application
    • 49
    • 38
    • 28
    • 27
    • 23
    • 20
    • 18
    • 13
    • 13
    • 9
    • 8
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TYR (NP_000363.1).
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TYR (Tyrosinase (TYR))
    Alternative Name
    TYR (TYR Products)
    Background
    The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
    Molecular Weight

    Observed_MW: 80 kDa

    Calculated_MW: 42 kDa/60 kDa

    Gene ID
    7299
    UniProt
    P14679
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