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Uromodulin antibody (AA 351-450)

UMOD Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IHC (fro), FACS, IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN678473
  • Target See all Uromodulin (UMOD) Antibodies
    Uromodulin (UMOD)
    Binding Specificity
    • 15
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivity
    • 56
    • 23
    • 20
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 44
    • 14
    • 6
    • 2
    Rabbit
    Clonality
    • 54
    • 12
    Polyclonal
    Conjugate
    • 33
    • 9
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Uromodulin antibody is un-conjugated
    Application
    • 53
    • 26
    • 21
    • 17
    • 13
    • 12
    • 12
    • 11
    • 10
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Cow
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from Human Uromodulin
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Cho, Song, Oh, Kim, Ko, Lee, Jo: "Fate of Neutrophils during the Recovery Phase of Ischemia/Reperfusion Induced Acute Kidney Injury." in: Journal of Korean medical science, Vol. 32, Issue 10, pp. 1616-1625, (2018) (PubMed).

    Kim, Ko, Lee, Kim, Jo, Cho: "Blocking junctional adhesion molecule C promotes the recovery of cisplatin-induced acute kidney injury." in: The Korean journal of internal medicine, Vol. 32, Issue 6, pp. 1053-1061, (2018) (PubMed).

  • Target
    Uromodulin (UMOD)
    Alternative Name
    Uromodulin (UMOD Products)
    Synonyms
    ADMCKD2 antibody, FJHN antibody, HNFJ antibody, HNFJ1 antibody, MCKD2 antibody, THGP antibody, THP antibody, urehr4 antibody, uromodulin antibody, UMOD antibody, Umod antibody
    Background

    Synonyms: ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, medullary cystic kidney disease 2 autosomal dominant, Tamm Horsfall glycoprotein, Tamm Horsfall urinary glycoprotein, Tamm-Horsfall urinary glycoprotein, THGP, THP, Umod, UROM_HUMAN, Uromodulin.

    Background: Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. Uromodulin, secreted form: Secreted into urine after proteolytical cleavage. Into the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals.

    Gene ID
    7369
    UniProt
    P07911
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