DPPA3 antibody (C-Term)
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- Target See all DPPA3 Antibodies
- DPPA3 (Developmental Pluripotency Associated 3 (DPPA3))
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Binding Specificity
- AA 134-170, C-Term
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DPPA3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This mouse Dppa3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 134-170 amino acids from the C-terminal region of mouse Dppa3.
- Clone
- RB51138
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DPPA3 Primary Antibody
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anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 1-159) antibody
DPPA3 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 101-159) antibodyDPPA3 Reactivity: Mouse, Pig WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 145-179), (C-Term) antibodyDPPA3 Reactivity: Human WB Host: Rabbit Polyclonal RB50716 unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 1-159) antibodyDPPA3 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 100-150) antibodyDPPA3 Reactivity: Human IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Developmental Pluripotency Associated 3 (DPPA3) (AA 1-159) antibodyDPPA3 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- DPPA3 (Developmental Pluripotency Associated 3 (DPPA3))
- Alternative Name
- Dppa3 (DPPA3 Products)
- Synonyms
- STELLA antibody, 2410075G02Rik antibody, PCG7 antibody, PGC7 antibody, Stella antibody, developmental pluripotency associated 3 antibody, developmental pluripotency-associated 3 antibody, DPPA3 antibody, Dppa3 antibody
- Background
- Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis.
- Molecular Weight
- 17670
- UniProt
- Q8QZY3
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