IFT57 antibody (Internal Region)
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- Target See all IFT57 Antibodies
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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Binding Specificity
- Internal Region
- Reactivity
- Human, Mouse, Rat, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IFT57 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- IFT57 Antibody detects endogenous levels of total IFT57.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human IFT57, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product IFT57 Primary Antibody
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anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 170-429) antibody
IFT57 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 1-429) antibodyIFT57 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 214-312) antibodyIFT57 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1G8 unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 159-193) antibodyIFT57 Reactivity: Human WB Host: Rabbit Polyclonal RB57869 unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) antibodyIFT57 Reactivity: Human, Mouse IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (Internal Region) antibodyVerified IFT57 Reactivity: Human, Mouse WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 214-312) antibodyIFT57 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
- Alternative Name
- IFT57 (IFT57 Products)
- Synonyms
- Esrrbl1 antibody, 4833420A15Rik antibody, Hippi antibody, MHS4R2 antibody, ESRRBL1 antibody, HIPPI antibody, intraflagellar transport 57 antibody, intraflagellar transport 57 S homeolog antibody, Ift57 antibody, IFT57 antibody, ift57.S antibody
- Background
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Description: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
Gene: IFT57
- Molecular Weight
- 49 kDa
- Gene ID
- 55081
- UniProt
- Q9NWB7
- Pathways
- Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
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