ALS2 antibody (C-Term)
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- Target See all ALS2 Antibodies
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
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Binding Specificity
- AA 1248-1277, C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ALS2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- Rat
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This ALS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2.
- Clone
- RB18853
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ALS2 Primary Antibody
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anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-280) antibody
ALS2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-280) antibodyALS2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 221-320) antibodyALS2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4F10 unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) antibodyALS2 Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (N-Term) antibodyALS2 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (C-Term) antibodyVerified ALS2 Reactivity: Human ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 221-321) antibodyALS2 Reactivity: Mouse WB Host: Mouse Monoclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-1237) antibodyALS2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1-1237) antibodyALS2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2) (AA 1007-1056) antibodyALS2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Bat, Chicken, Monkey WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
- Alternative Name
- ALS2 (ALS2 Products)
- Synonyms
- als2 antibody, si:dkey-33m14.1 antibody, ALS2CR6 antibody, ALSJ antibody, IAHSP antibody, PLSJ antibody, 3222402C23Rik antibody, 9430073A21Rik antibody, Als2cr6 antibody, Alsin antibody, mKIAA1563 antibody, amyotrophic lateral sclerosis 2a (juvenile) antibody, alsin antibody, ALS2, alsin Rho guanine nucleotide exchange factor antibody, amyotrophic lateral sclerosis 2 (juvenile) antibody, als2a antibody, CpipJ_CPIJ008258 antibody, CpipJ_CPIJ008260 antibody, ALS2 antibody, Als2 antibody
- Background
- ALS2 contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.
- Molecular Weight
- 183634
- Gene ID
- 57679
- NCBI Accession
- NP_001129217, NP_065970
- UniProt
- Q96Q42
- Pathways
- Skeletal Muscle Fiber Development
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