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USP16 antibody (N-Term)

USP16 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265912
  • Target See all USP16 Antibodies
    USP16 (Ubiquitin Specific Peptidase 16 (USP16))
    Binding Specificity
    • 15
    • 14
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 55
    • 11
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    Human, Mouse, Rat
    Host
    • 51
    • 3
    • 1
    Rabbit
    Clonality
    • 54
    • 1
    Polyclonal
    Conjugate
    • 23
    • 6
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP16 antibody is un-conjugated
    Application
    • 44
    • 32
    • 15
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    USP16 Antibody detects endogenous levels of total USP16.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human USP16, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    USP16 (Ubiquitin Specific Peptidase 16 (USP16))
    Alternative Name
    USP16 (USP16 Products)
    Synonyms
    ubp-m antibody, USP16 antibody, UBP-M antibody, 1200004E02Rik antibody, 2810483I07Rik antibody, 6330514E22Rik antibody, UBPM antibody, si:ch211-238e22.5 antibody, si:dkey-121n8.2 antibody, wu:fc76b02 antibody, wu:fc76b08 antibody, universal stress protein antibody, ubiquitin specific peptidase 16 antibody, ubiquitin specific peptidase 16 L homeolog antibody, usp16 antibody, USP16 antibody, Usp16 antibody, usp16.L antibody
    Background

    Description: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.

    Gene: USP16

    Molecular Weight
    94 kDa
    Gene ID
    10600
    UniProt
    Q9Y5T5
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