VEGFC Protein (AA 103-227) (His-Avi Tag)
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- Target See all VEGFC Proteins
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 103-227
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VEGFC protein is labelled with His-Avi Tag.
- Purpose
- Human VEGF-C/Flt4-L Protein
- Sequence
- Thr103-Arg227
- Characteristics
- Recombinant Human VEGF-C/Flt4-L Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Thr103-Arg227.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human VEGF-C, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human VEGF R3, hFc Tag with the EC50 of 19.8ng/ml determined by ELISA. The affinity constant of 0.29 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) protein (His-Avi Tag,Biotin)
VEGFC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Vascular Endothelial Growth Factor C (VEGFC) (AA 1-419) protein (GST tag)VEGFC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Vascular Endothelial Growth Factor C (VEGFC) (AA 103-227) protein (His tag)VEGFC Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) protein (GST tag)VEGFC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) protein (His tag)Crystallography grade VEGFC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227), (full length) protein (GST tag)VEGFC Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 50 mM MES, 150 mM NaCI ( pH 6.0).
- Buffer
- Lyophilized from 0.22μm filtered solution in 50 mM MES, 150 mM NaCl ( pH 6.0). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
- Alternative Name
- VEGF-C (VEGFC Products)
- Synonyms
- VEGFC Protein, vegf-c Protein, xvegf-c Protein, Flt4-L Protein, VRP Protein, AW228853 Protein, VEGF-C Protein, vascular endothelial growth factor c Protein, vascular endothelial growth factor C Protein, vascular endothelial growth factor C S homeolog Protein, vegfc Protein, VEGFC Protein, vegfc.S Protein, Vegfc Protein
- Background
- The lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not VEGFD, a finding consistent with high expression of VEGFC in both platelets and avian thrombocytes.
- Molecular Weight
- 17.1 kDa. Due to glycosylation, the protein migrates to 23-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q6FH59
- Pathways
- RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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