YES1 antibody (AA 1-155)
-
- Target See all YES1 Antibodies
- YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))
-
Binding Specificity
- AA 1-155
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This YES1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Tyrosine-protein kinase Yes protein (1-155AA)
- Isotype
- IgG
-
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (pTyr426) antibody
YES1 Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-80) antibodyYES1 Reactivity: Human WB, ELISA, PLA Host: Mouse Monoclonal 3C6 unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-543) antibodyYES1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2D5 unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 441-541) antibodyYES1 Reactivity: Human, Mouse WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 284-541) antibodyYES1 Reactivity: Human, Mouse WB, IHC, IHC (p), IF, ICC Host: Rabbit Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (Center) antibodyYES1 Reactivity: Human, Mouse WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-543) antibodyYES1 Reactivity: Human WB, ELISA, RNAi Host: Mouse Monoclonal 2F4 unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) antibodyYES1 Reactivity: Human, Dog, Zebrafish (Danio rerio) WB, IHC (p), IF Host: Rabbit Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-30), (N-Term) antibodyYES1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB3091 unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 10-193) antibodyYES1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2F3E6 unconjugated
-
- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))
- Alternative Name
- YES1 (YES1 Products)
- Synonyms
- HsT441 antibody, P61-YES antibody, Yes antibody, c-yes antibody, yes antibody, p61-Yes antibody, hst441 antibody, p61-yes antibody, YES antibody, c-Yes antibody, p60c-yes antibody, YES proto-oncogene 1, Src family tyrosine kinase antibody, YES proto-oncogene 1, Src family tyrosine kinase L homeolog antibody, YES1 antibody, yes1.L antibody, yes1 antibody, Yes1 antibody
- Background
-
Background: Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis.
Aliases: c Yes antibody, Cellular Yes 1 protein antibody, Cellular Yes1 protein antibody, HsT441 antibody, P61 YES antibody, p61-Yes antibody, Proto oncogene tyrosine protein kinase YES antibody, Proto-oncogene c-Yes antibody, Tyrosine-protein kinase Yes antibody, v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody, Viral oncogene yes 1 homolog 1 antibody, Viral oncogene yes1 homolog 1 antibody, Yamaguchi sarcoma oncogene antibody, Yes 1 antibody, Yes antibody, YES proto oncogene 1, Src family tyrosine kinase antibody, YES_HUMAN antibody, YES1 antibody, YES1 proto oncogene, Src family tyrosine kinase antibody
- UniProt
- P07947
- Pathways
- CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
-
