EP400 antibody (AA 1051-1250)
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- Target See all EP400 Antibodies
- EP400 (E1A Binding Protein P400 (EP400))
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Binding Specificity
- AA 1051-1250
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EP400 antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human p400
- Isotype
- IgG
- Top Product
- Discover our top product EP400 Primary Antibody
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anti-E1A Binding Protein P400 (EP400) (AA 743-850) antibody
EP400 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2A7 unconjugated
anti-E1A Binding Protein P400 (EP400) (AA 1-985) antibodyEP400 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-E1A Binding Protein P400 (EP400) (AA 90-330) antibodyEP400 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- EP400 (E1A Binding Protein P400 (EP400))
- Alternative Name
- P400 (EP400 Products)
- Synonyms
- CAGH32 antibody, P400 antibody, TNRC12 antibody, 1700020J09Rik antibody, AU023439 antibody, mDomino antibody, mKIAA1498 antibody, p400 antibody, E1A binding protein p400 antibody, EP400 N-terminal-like protein antibody, helicase domino antibody, E1a binding protein P400 antibody, EP400 antibody, Ep400 antibody, LOC738562 antibody, LOC5570719 antibody, CpipJ_CPIJ007689 antibody, CpipJ_CPIJ007688 antibody, CpipJ_CPIJ007686 antibody, CpipJ_CPIJ008061 antibody
- Background
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Synonyms: CAG repeat protein 32, CAGH32, DKFZP434I225, Domino homolog, E1A binding protein p400, EP 400, EP400, FLJ42018, FLJ45115, hDomino, KIAA1498, KIAA1818, p400 kDa SWI2/SNF2 related protein, P400 SWI2/SNF2-related protein, TNRC12, Trinucleotide repeat containing 12, Trinucleotide repeat containing gene 12 protein, EP400_HUMAN.
Background: NuAR is a multi-protein histone acetyltransferase complex that functions to acetylate the nucleosomal Histones H4 and H2A, thereby activating transcription of select target genes. p400, also known as EP400 (E1A binding protein p400) or mDomino, localizes to the nucleus and is a component of the NuAR complex. Expressed in brain, liver, thymus, lung, spleen, colon and kidney, p400 regulates the transcriptional activity of proteins such as MZF-1 and contributes to the ATPase and helicase activities of NuA4. p400 is a SWI2/ SNF2-related protein that can interact with the adenovirus oncoprotein E1A, thus activating the proapoptotic activity of E1A. The ability of p400 to regulate transcriptional and apoptotic activity suggests that the NuAR complex may be a crucial component of cell proliferation, transformation and, possibly, carcinogenesis. Five isoforms of p400 exist due to alternative splicing events.
- Gene ID
- 57634
- Pathways
- Chromatin Binding
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