CA8 antibody
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- Target See all CA8 Antibodies
- CA8 (Carbonic Anhydrase VIII (CA8))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CA8 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant full-length human CA8 protein
- Clone
- CPTC-CA8-2
- Isotype
- IgG2a kappa
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anti-Carbonic Anhydrase VIII (CA8) (AA 1-290) antibody
CA8 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 40-139) antibodyCA8 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1F7 unconjugated
anti-Carbonic Anhydrase VIII (CA8) (C-Term) antibodyCA8 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 40-139) antibodyCA8 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 31-80) antibodyCA8 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Monkey, Rabbit, Guinea Pig, Bat, Chicken, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (C-Term) antibodyCA8 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Monkey, Rabbit, Guinea Pig, Bat, Chicken, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 1-290) antibodyCA8 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (Center) antibodyCA8 Reactivity: Human, Mouse, Rat, Cow, Monkey WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Carbonic Anhydrase VIII (CA8) (AA 1-290) antibody (APC)CA8 Reactivity: Human IHC, ICC, FACS, IF Host: Rabbit Polyclonal APC
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- Application Notes
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Positive Control: Human cerebellum. Selective expression in purkinje cells. HEK-293 and K-562 cell lines.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- CA8 (Carbonic Anhydrase VIII (CA8))
- Alternative Name
- CA8 (CA8 Products)
- Synonyms
- AW546993 antibody, Ca8 antibody, Cals antibody, Cals1 antibody, Carp antibody, wdl antibody, zgc:110118 antibody, CA-VIII antibody, CALS antibody, CAMRQ3 antibody, CARP antibody, carbonic anhydrase 8 antibody, carbonic anhydrase VIII antibody, CAH8 antibody, Car8 antibody, ca8 antibody, CA8 antibody
- Background
- The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.
- Molecular Weight
- 32.97kDa
- Gene ID
- 767
- UniProt
- P35219
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