Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PRDM2 antibody (AA 1-347)

PRDM2 Reactivity: Human, Mouse WB, ChIP Host: Mouse Monoclonal 33AT1045 unconjugated
Catalog No. ABIN387783
  • Target See all PRDM2 Antibodies
    PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
    Binding Specificity
    • 15
    • 15
    • 9
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-347
    Reactivity
    • 63
    • 13
    • 12
    Human, Mouse
    Host
    • 54
    • 12
    Mouse
    Clonality
    • 55
    • 11
    Monoclonal
    Conjugate
    • 19
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PRDM2 antibody is un-conjugated
    Application
    • 40
    • 30
    • 26
    • 26
    • 21
    • 16
    • 8
    • 6
    • 3
    • 2
    • 2
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This antibody is specific for RIZ1, it does not recognize the isoform beta (RIZ2).
    Clone
    33AT1045
    Isotype
    IgG1
  • Application Notes
    CHIP: 1:100. CHIP: 1:100. CHIP: 1:100. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Lakshmikuttyamma, Takahashi, Pastural, Torlakovic, Amin, Garcia-Manero, Voralia, Czader, DeCoteau, Geyer: "RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression." in: Journal of hematology & oncology, Vol. 2, pp. 28, (2009) (PubMed).

    Carling, Kim, Yang, Gu, Zhang, Huang: "A histone methyltransferase is required for maximal response to female sex hormones." in: Molecular and cellular biology, Vol. 24, Issue 16, pp. 7032-42, (2004) (PubMed).

  • Target
    PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
    Alternative Name
    PRDM2 (RIZ1) (PRDM2 Products)
    Synonyms
    MGC114763 antibody, prdm2 antibody, riz antibody, kmt8 antibody, riz1 antibody, riz2 antibody, mtb-zf antibody, humhoxy1 antibody, PRDM2 antibody, HUMHOXY1 antibody, KMT8 antibody, MTB-ZF antibody, RIZ antibody, RIZ1 antibody, RIZ2 antibody, 4833427P12Rik antibody, E330024L24Rik antibody, Gm1033 antibody, Gm19732 antibody, Riz antibody, Riz1 antibody, Znfpr1c1 antibody, PR domain containing 2, with ZNF domain S homeolog antibody, PR domain containing 2, with ZNF domain b antibody, PR domain containing 2, with ZNF domain antibody, PR domain zinc finger protein 2 antibody, PR/SET domain 2 antibody, prdm2.S antibody, prdm2b antibody, prdm2 antibody, LOC100350859 antibody, PRDM2 antibody, Prdm2 antibody
    Background
    This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    188915
    Gene ID
    7799
    NCBI Accession
    NP_001007258, NP_001129082, NP_036363, NP_056950
    UniProt
    Q13029
You are here:
Support