BIRC7 antibody (AA 101-200)
(2 references)-
- Target See all BIRC7 Antibodies
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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Binding Specificity
- AA 101-200
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BIRC7 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Livin
- Isotype
- IgG
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anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibody
BIRC7 Reactivity: Human WB, IHC (p), IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 264-280) antibodyBIRC7 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 271-298), (C-Term) antibodyBIRC7 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB1799-1800 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyVerified BIRC7 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 264-280) antibodyBIRC7 Reactivity: Human, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-90) antibodyBIRC7 Reactivity: Human ELISA, IF Host: Mouse Monoclonal 3H1 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 Reactivity: Human WB, IHC (p), IP, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 87-298) antibodyBIRC7 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 Reactivity: Human WB, IF, FACS Host: Mouse Monoclonal 1B10 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyBIRC7 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." in: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).
: "Prospective experimental studies on the renal protective effect of ulinastatin after paraquat poisoning." in: World journal of emergency medicine, Vol. 3, Issue 4, pp. 299-304, (2014) (PubMed).
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: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." in: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).
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- Target
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
- Alternative Name
- Livin (BIRC7 Products)
- Synonyms
- KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody
- Background
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Synonyms: KIAP, LIVIN, MLIAP, RNF50, ML-IAP, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, RING finger protein 50, BIRC7, UNQ5800/PRO19607/PRO21344
Background: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
- Gene ID
- 79444
- UniProt
- Q96CA5
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