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CHMP6 antibody (AA 2-201)

CHMP6 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7147533
  • Target See all CHMP6 Antibodies
    CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
    Binding Specificity
    • 14
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 2-201
    Reactivity
    • 27
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 2
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    This CHMP6 antibody is un-conjugated
    Application
    • 27
    • 18
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Charged multivesicular body protein 6 protein (2-201AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
    Alternative Name
    CHMP6 (CHMP6 Products)
    Synonyms
    chmp6 antibody, vps20 antibody, 2400004G01Rik antibody, VPS20 antibody, RGD1565325 antibody, chmp6l antibody, flj11749l antibody, wu:fb79d02 antibody, zgc:110067 antibody, charged multivesicular body protein 6 antibody, charged multivesicular body protein 6 L homeolog antibody, charged multivesicular body protein 6 S homeolog antibody, charged multivesicular body protein 6b antibody, LOC100280982 antibody, chmp6.L antibody, chmp6.S antibody, CHMP6 antibody, chmp6 antibody, Tsp_08316 antibody, Chmp6 antibody, chmp6b antibody
    Background

    Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.

    Aliases: Charged multivesicular body protein 6 antibody, chmp6 antibody, CHMP6_HUMAN antibody, Chromatin modifying protein 6 antibody, Chromatin-modifying protein 6 antibody, FLJ11749 antibody, hVps 20 antibody, hVps20 antibody, novel SNF7 protein antibody, OTTMUSP00000004363 antibody, RGD1565325 antibody, RP24 225K18.4 antibody, Vacuolar protein sorting associated protein 20 antibody, Vacuolar protein sorting-associated protein 20 antibody, Vps 20 antibody, Vps20 antibody

    UniProt
    Q96FZ7
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