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TUSC3 antibody (AA 42-196)

TUSC3 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7173930
  • Target See all TUSC3 Antibodies
    TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))
    Binding Specificity
    • 15
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 42-196
    Reactivity
    • 27
    • 20
    • 5
    • 1
    • 1
    Human
    Host
    • 26
    • 1
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TUSC3 antibody is un-conjugated
    Application
    • 24
    • 13
    • 13
    • 11
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Tumor suppressor candidate 3 protein (42-196AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))
    Alternative Name
    TUSC3 (TUSC3 Products)
    Synonyms
    zgc:110044 antibody, D8S1992 antibody, M33 antibody, MRT22 antibody, MRT7 antibody, N33 antibody, OST3A antibody, AU022242 antibody, BC003311 antibody, tumor suppressor candidate 3 antibody, tumor suppressor candidate 3 L homeolog antibody, TUSC3 antibody, tusc3 antibody, tusc3.L antibody, CpipJ_CPIJ005611 antibody, Tusc3 antibody
    Background

    Background: Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues, in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.

    Aliases: TUSC3 antibody, N33Tumor suppressor candidate 3 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3 antibody, Oligosaccharyl transferase subunit TUSC3 antibody, Magnesium uptake/transporter TUSC3 antibody, Protein N33 antibody

    UniProt
    Q13454
    Pathways
    Cell RedoxHomeostasis
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